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Talk to Cancer Specialist / Oncologist on Moderately Differentiated Adenocarcinoma G2

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Asking for Mother, Female, 68 years old, Lahore

My mother recently went through Gallbladder Lap. Chole. And pathology report revealed Moderately Differentiated G2 Adenocarcinoma. Oncoligist further suggested few tests including PET CT Scan and the results are below. CA19.9------16.42 CA-125------16.9 CEA------1.49 PET SCAN findings revealed Metabolically active INTRA-thoracic lymph nodes are concerning for Metastatic disease. Hypermetabolic lymph node measures 11mm is observed in descending aorto-esopageal recess likely Metastatic. Now what should be next procedure? Is it curable. I am attaching the reports.

Cancer Specialist / Oncologist in Lahore - Dr. Muhammad Arif Ch

Dr. Muhammad Arif Ch - Cancer Specialist / Oncologist

MBBS, Diplomate American Board of Medical Oncology, Diplomate American Board of Hematology, Diplomate American Board of Internal Medicine | Lahore

Thank you for the information. It's not curable. If she is in good physical condition,  she could be treated with chemotherapy and it helps some patients .

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At what stage her cancer is? How much time she has medically?

5 years ago

Cancer Specialist / Oncologist in Lahore - Dr. Amjad Sk Durrani

Dr. Amjad Sk Durrani - Cancer Specialist / Oncologist

MBBS, AFSA (Medical Oncology), DMRT (Diploma in Medical Radiology Therapeutics) | Lahore

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703 Positive Reviews

Thank you for your mail.As a matter of fact decision is not straight  forward.Since a couple active lymph nodes are localised on PET then lymphadenetomy( removal of lymph nodes and sending for histopathology to prove it is a metastatic disease ) if not then no need for chemotherapy.If positive yes.But it is quite difficult surgery at times.The other approach is to give chemotherapy and Radiotherapy (for local area of gall bladder surgery). After completing chemotherapy perform PET again to see results.if ok means no active nodes then follow  with PET or CT over the period of 5 years.  

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Post Owner


At what stage her cancer is? how much time she has medically?

5 years ago

Cancer Specialist / Oncologist in Karachi - Dr. Mariam Gul

Dr. Mariam Gul - Cancer Specialist / Oncologist

MBBS, D.M.R.T. (Medical Radio Therapy) | Karachi

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293 Positive Reviews

Very complex situation. Disease is metastasised, but if patients general condition is good , she can be given chemotherapy,,, unfortunately chances are not very high.

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Thanks doc. For your valuable input. At what stage her cancer is?

5 years ago

Cancer Specialist / Oncologist in Lahore - Prof. Dr. Abbas Khokhar

Prof. Dr. Abbas Khokhar - Cancer Specialist / Oncologist

MBBS, FCPS (Medical Oncology), MD (USA), DHHM | Lahore

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190 Positive Reviews

Its stage 4. I agree with the opinion of all the other learned oncologist

Cancer Specialist / Oncologist in Karachi - Dr. Abdul Qayyum

Dr. Abdul Qayyum - Cancer Specialist / Oncologist

MBBS, MCPS (Therapeutic Radiology), MD (Oncology) | Karachi

The guideline for gallbladder cancer surgery is wide local excision with removal of all related lymph nodes. In this case laparoscopic surgery was done and lymph nodes were not recovered in pathological specimen. PET Scan revealed metastatic thoracic lymph nodes. These lymph nodes should be confirmed for mets. (but it is v difficult). Otherwise chemotherapy can be given, which will be some helpful.

Cancer Specialist / Oncologist in Faisalabad - Dr. Rana Qamar Javed

Dr. Rana Qamar Javed - Cancer Specialist / Oncologist

| MBBS | MD | MCPS (Medicine) | FCPS (Medical Oncology) | Member Of European Society Of Medical Oncology | | Faisalabad

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168 Positive Reviews

It's very interesting. Usually disease go nearby Lymph nodes but in this case metabolic activity is found intra thoracic. if we consider it as metastasis, cure is not possible unfortunately but there are new drugs available which can shrink this cancer and let patient live some longer

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