As with many drugs, aspirin can have unwanted effects, albeit not everyone experiences them. The shortest amount of time at the lowest dose that works for you is preferable. You have a lower probability of experiencing adverse side effects if you do this. Here we would discuss Stomach Ulcer from Aspirin; So don’t go anywhere sit and read our segment.
Ulcer and Aspirin
More than 1 in 100 people experience these aspirin-related adverse effects. You can take steps to assist yourself deal with them. If the adverse effects annoy you or do not go away, speak with your doctor or pharmacist.
Serious side effects of Aspirin
Rarely, but occasionally, taking aspirin can cause major side effects in some people. If any of the following apply:
- The whites of your eyes change yellow, your skin turns yellow (this may be less visible on brown or black skin), or your pee gets darker—these symptoms could indicate liver problems.
- You cough up blood, have blood in your poop, pee, or vomit.
- You have aching joints in your hands and feet, which may indicate that there is too much uric acid in your blood. You have swollen hands or feet, which may indicate water retention.
Stomach Ulcers
If you take aspirin frequently or in high amounts, it can lead to stomach or intestinal ulcers. If you now have or have ever had a stomach ulcer, your doctor may advise against using aspirin.
Take paracetamol instead of aspirin if you have a stomach ulcer risk and need pain relief because it is gentler on the stomach. Click here to consult online with the Best Gastroenterologists in your city via Marham.
Serious allergic reaction
Anaphylaxis, a severe allergic reaction, can occasionally occur after using aspirin.
Detailed study by Researchers on Aspirin and Stomach Ulcers
For both primary and secondary prevention of cardiovascular thromboembolic events, low dose aspirin is used. Aspirin is a non-selective cyclooxygenase inhibitor, and its usage impairs platelet aggregation by irreversibly inhibiting COX-1.
However, aspirin also reduces the production of anti-inflammatory prostaglandins in the gastrointestinal mucosa, inhibiting COX-1 activity there. As a result, gastrointestinal ulcers associated with aspirin and its consequences are more likely to occur.
A significant number of people who take aspirin also need to take anti-inflammatory drugs concurrently to treat their pain and arthritis.
However, research indicates that using aspirin along with other nonselective NSAIDs greatly increases the chance of developing gastroduodenal ulcers and ulcer complications.
An earlier study found that compared to aspirin alone, concurrent aspirin (325 mg daily) in healthy participants taking naproxen (500 mg bid) was related with an endoscopic ulcer rate of 27.3%. (7.6 percent ). Patients utilising 81 mg of aspirin daily together with naproxen experienced a greater incidence of gastric and duodenal ulcers than those receiving aspirin therapy alone in a different, independent experiment with a comparable design.
Along with endoscopic ulcer rates, low-dose aspirin combined with nonselective NSAIDS has been shown to significantly increase the risk of upper gastrointestinal bleeding. These findings imply that the gastrointestinal toxicity of aspirin and other NSAIDs in combination may go beyond additive.
Precautions
Utilizing over-the-counter pain relievers ought to be done with extreme caution if you have an ulcer. Keep in mind that no medicine is risk-free. If you have an ulcer or other medical concerns, it is crucial to discuss the usage of OTC medications with your doctor. Here are some advice from the professionals on how to use these medications properly.
- Avoid using NSAIDs (non-steroidal anti-inflammatory drugs). Use of NSAIDs, such as aspirin or ibuprofen. It might be safer to choose a non-NSAID pain treatment like acetaminophen. Your doctor can suggest suitable substitutes.
- Take safety measures. To make it easier on your stomach if you must use an NSAID, always take it with milk or food . Your doctor may advise using a prescription proton pump inhibitor, such as Prilosec, Prevacid, Aciphex.
- High doses of prescription H2 receptor antagonists, such as Pepcid, Tagamet, Axid
Book your appointment with the Best Gastroenterologists in Pakistan online via Marham today!
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FAQ’s
Can aspirin cause an ulcer?
If you use aspirin frequently or at high amounts, it is more likely to result in stomach or intestinal ulcers. If you now have or have ever had a stomach ulcer, your doctor may advise against using aspirin.
Should I stop taking aspirin if I have an ulcer?
The risk of stomach or intestinal bleeding or ulcers is higher in people who take aspirin regularly to prevent heart attacks or strokes. You can still take aspirin if you’ve already had an ulcer; just talk to your doctor about the risks and rewards first.
How much aspirin can cause ulcer?
Patients using 81 mg of aspirin along with daily naproxen also experienced a greater incidence of gastric and duodenal ulcers than aspirin therapy alone in a different, independent trial with a comparable design.